Sinusitis Overview & Treatments

Sinusitis affects 35 million people each year (inflation adjusted),1 making it one of the most common health problems in the U.S. It is more prevalent than heart disease and asthma1 and has a greater impact on one’s quality of life than chronic back pain or congestive heart failure.2

Sinusitis is defined as an inflammation of the sinus lining, and is commonly caused by structural issues such as ostial blockage, bacterial infections, viral infections or a combination of these. For many patients, symptoms vary and may include nasal congestion, facial discomfort, nasal discharge, headache and fatigue. Sinusitis is considered acute when symptoms last 4 weeks or less and chronic when it lasts 12 weeks or longer.3

Treatment Options

The most common treatments for sinusitis aim to reduce mucosal swelling and relieve obstructions within the sinus ostium and ostio-meatal region, and include:

  • Medical therapy with antibiotics
  • Topical nasal steroid spray

However, at least 20 percent of patients do not respond adequately to medications.4-6

For patients who have failed medical therapy, Endoscopic Sinus Surgery (ESS) is often the next step toward finding relief. During ESS, surgical instruments are used to remove small amounts of bone, tissue or growth blocking the sinus openings. Often, this removal of bone and tissue can require uncomfortable nasal packing after surgery and lead to post-surgery pain and scarring.

A Significant Unmet Clinical Need

Each year approximately 1,250,000 patients are left living with their sinus condition.6-9 These patients may not find adequate relief from medical therapy and are candidates for surgery, but for a variety of clinical or personal reasons choose not to undergo ESS using existing surgical instruments.

Balloon Sinuplasty Technology: Novel, Endoscopic, Catheter-Based Devices

Balloon Sinuplasty products are endoscopic, catheter-based devices used to dilate blocked paranasal sinus ostia. These devices are endoscopic tools that may be used with other medical therapies or ESS techniques. Learn more about the Balloon Sinuplasty technology.

1. Benninger, M. et al. Adult chronic rhinosinusitis: Definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngology Head Neck Surg 2003; 129S: S1-S32.
2. Gliklich, R., et al. Health impact of chronic sinusitis in patients seeking otolaryngologic care. Journal of Allergy and Clinical Immunology 1995; 113: 104-109.
3. Sinusitis - Patient Health Information. American Academy of Otolaryngology - Head and Neck Surgery. 2016.
4. Stankiewicz, J., et al. Cost analysis in the diagnosis of chronic rhinosinusitis. American Journal of Rhinology 2003; 17(3): 139-142.
5. Subramanian, H., et al. A retrospective analysis of treatment outcomes and time to relapse after intensive medical treatment for CRS. American Journal of Rhinology 2002; 16(6): 303-312.
6. Rosenfeld, R.M., Piccirillo, J.F., Chandrasekhar, S.S., et al. (2015), Clinical Practice Guideline (Update): Adult Sinusitis, Otolaryngology - Head and Neck Surgery, 152(25): S1-S39.
7. National Ambulatory Medical Care Survey: 2009 Summary Tables Table 13 (CDC)
8. Lal, D., Scianna, J., Stankiewicz, J. (2009). Efficacy of Targeted Medical Therapy in Chronic Rhinosinusitis, and Predicators of Failure. Am J Rhinol (21): 11-18.
9. Hessler, J., et al. Clinical outcomes of chronic rhinosinusitis in response to medical therapy: Results of a prospective study. American Journal of Rhinolology 2007; 21(1): 10-18.


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